Health officials in Ghana are urging the public to be vigilant as Mpox cases in the country have climbed to 133, with 14 new infections recently identified nationwide. This surge, based on the latest update from the Ghana Health Service (GHS) released on Wednesday, June 25, 2025, has prompted immediate and determined action from the Ministry of Health. Both entities are now working tirelessly to contain the outbreak and prevent any further spread.
Despite the concerning rise in confirmed Mpox cases, there’s a glimmer of good news: the GHS confirmed in a report on June 30, 2025, that no new deaths or hospital admissions have been reported. All patients are currently being managed as outpatients across various hospitals, meaning their conditions are stable enough not to require inpatient care.
The increase in cases is particularly noticeable in the Greater Accra Region, where the majority of infections have been found. However, the virus has now spread, with cases detected in 46 districts across 10 regions of Ghana. These include the Western, Western North, Central, Ashanti, Volta, Eastern, Bono, North East, and Northern Regions, highlighting the widespread nature of the current situation.
These latest figures show a consistent climb from the previous update on June 20, 2025, when 10 new Mpox cases brought the total to 119. Authorities are now doubling down on their efforts, focusing on intensified community surveillance, thorough contact tracing, and targeted vaccination initiatives, specifically aiming at high-risk groups, to help curb this escalating situation.

Despite the surge, health authorities maintain, “The situation remains under control, with no severe complications or fatalities reported thus far.”
Mpox vaccination is advised for individuals identified as being at higher risk, even though the majority of cases typically only need supportive care. For more severe instances, healthcare providers may choose to administer antiviral medications.
The Ghana Health Service has urged the public to “take precautions and report early symptoms to minimise the risk of further transmission.”
Public health campaigns are being stepped up to teach everyone about the virus and encourage simple ways to stay safe. This includes things like washing hands regularly, avoiding close contact with people who show symptoms, and getting immediate medical help if you notice any unexplained rash, especially if it comes with a fever and swollen lymph nodes.
In a show of international support, the World Health Organisation (WHO) on June 24, 2025, generously donated test kits and laboratory reagents to the National Public Health Reference Laboratory in Accra. This important donation includes enough supplies to screen 3,400 suspected cases and test 625 confirmed samples for various virus subtypes. This will significantly boost Ghana’s ability to respond to this viral disease across the nation.
The government is urging citizens to “stay informed, seek medical attention if symptoms arise, and adhere to the guidelines issued by health professionals.”